Deep, specific future-era sequencing has unveiled that subclonal mutations (i.e., Individuals present in just a fraction of tumor cells) is usually detected for all driver genes and so are related to quick disorder progression and inadequate final result.eleven–thirteen This is especially relevant for TP53
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ないことが問題となっている.そこで本稿では，アプリケーションが送信するデータのペイロードサイズによってデ
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mutations, missing their negative outcome in individuals dealt with with VO. The one factor that remained predictive of a shorter development-free of charge survival On this cohort of individuals was TP53
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) and incorporated into these prognostic techniques, but none of those makes an attempt succeeded in getting to be standard of treatment.94–96 Certainly, the Worldwide Workshop on CLL (iwCLL) suggestions only propose analyzing the IGHV status and LINK ALTERNATIF MBL77 presence/absence of TP53 aberrations in regimen practice.
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